ADME/DMPK Science and
Strategies to support Drug
Development

Detection of liabilities

Reduction of drug candidate failure

DDI risk mitigation

Screening for diverse PK liabilities in chemical
series, understanding tool compound/s
Profiling & Modeling of human PK and mechanistic
understanding of human PK, Risk assessments
Outlining/Recommending when to do which study, be the discussion partner with CROs and to interpret data
Support to design studies at CROs, evaluating CROs, checking study protocol and study reports, as well as writing reports
Support to mechanistic understanding of Clinical candidates, of their human PK as well as DDI risk assessments and mitigation